Nucleotide composition-linked divergence of vertebrate core promoter architecture
نویسندگان
چکیده
منابع مشابه
Nucleotide composition-linked divergence of vertebrate core promoter architecture.
Transcription initiation involves the recruitment of basal transcription factors to the core promoter. A variety of core promoter elements exists; however for most of these motifs, the distribution across species is unknown. Here we report on the comparison of human and amphibian promoter sequences. We have used oligo-capping in combination with deep sequencing to determine transcription start ...
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The stress response involves complex physiological mechanisms that maximize behavioral efficacy during attack or defense and is highly conserved in all vertebrates. Key mediators of the stress response are pituitary hormones encoded by the proopiomelanocortin gene (POMC). Despite conservation of physiological function and expression pattern of POMC in all vertebrates, phylogenetic footprinting ...
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ژورنال
عنوان ژورنال: Genome Research
سال: 2011
ISSN: 1088-9051
DOI: 10.1101/gr.111724.110